After an 'incident' one wet Friday night where Professor Andrew Martin is found walking naked through the streets of Cambridge, he is not feeling quite himself. Food sickens him. Clothes confound him. Even his loving wife and teenage son are repulsive to him. He feels lost amongst a crazy alien species and hates everyone on the planet. Everyone, that is, except Newton, and he's a dog. What could possibly make someone change their mind about the human race. . . ?